Association analysis of polymorphisms in <em>STARD6</em> and near <em>ECHDC3</em> in Alzheimer’s disease patients carrying the <em>APOE</em> ε4 Allele
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چکیده
منابع مشابه
ASSOCIATION STUDY OF MIR-146A RS2910164 AND RS57095329 POLYMORPHISMS WITH RISK OF BEHCET’S DISEASE
Background & Aims: Behcet's disease (BD) is an autoimmune disease that usually occurs with oral, genital and ocular ulcers. The cause of this disease is unknown and environmental, genetic and immunological factors contribute to its development. In the present study, the relation between rs2910164 and rs57095329 polymorphisms of miR146a gene with the potential for BD was investigated in Iranian ...
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Chemokines participate in the regulation of immune and inflammatory responses by interacting with their specific receptors on related immune and inflammatory cells such as B-lymphocytes, T-lymphocytes and antigen-presenting cells. Chemokines and their receptors are therefore considered to mediate inflammation and tissue damage in autoimmune disorders. The recent studies have revealed the genoty...
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Introduction: Schizophrenia is a chronic heterogenic neurodevelopment disorder. Many genes interfere in the development of SCZ. All four genes, NrCAM, PRODH, ANK3, and ANKK1, which were evaluated in this study, were previously reported to be associated with Schizophrenia. The NrCAM contributes to creating cognitive deficiencies through the CAM’s signaling pathway. PRODH plays a vital role in cr...
متن کاملMajor decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E epsilon4 allele.
OBJECTIVE Recent evidence indicates that the apolipoprotein E (ApoE) epsilon4 allele is a risk factor for developing Alzheimer's disease. It has also been proposed that it is associated with increased counts of amyloid plaques and neurofibrillary tangles that in turn are neuropathological hallmarks initially appearing in the medial temporal lobe structures in Alzheimer's disease. In this study,...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2019
ISSN: 1178-2021
DOI: 10.2147/ndt.s186705